M/s submitted to Chemistry in Britain.

Please address all correspondence to:

Prof Mark J Winter
Department of Chemistry
The University of Sheffield
Sheffield S3 7HF, UK.


Modification Date: Wednesday, March 29, 1995

Chemistry and the WWW

Henry S Rzepa, Benjamin J Whitaker, and Mark J Winter

Department of Chemistry, Imperial college, London, SW7 2AY, UK
School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
Department of Chemistry, The University of Sheffield, Sheffield S3 7HF, UK

Box2: Hyperlinking Chemistry

Several mechanisms exist for extending World Wide Web hyperlinks beyond simple text to two and three dimensional molecular structures. One such involves a mapping technique in which hyperlinks can appear to be associated with two-dimensional chemical features such as atoms, bonds or functional groups. In the example below, the synthetic strategy leading to the synthesis of papuamine[1] is explored via two-dimensional retrosynthetic scheme. This diagram has a number of defined "hotspots" involving selected functional groups and the reagents involved in each transformation. When activated with a press of the mouse button, these hyperlinks provide the user with further details of each step. The effect is to avoid excessive detail in the original diagram by presenting only the main points, whilst still retaining an access mechanism for the detail.

One application of such a display would be an electronic poster, examples of which are to be found in the Electronic Conference on Trends in Organic Chemistry,[2] or the very successful ECCC conference from November 1994.[3]